Citicoline Studies

According to a study published in The Journal of Nutrition, dietary supplementation of Cognizin® citicoline for 12 weeks improved overall memory performance, especially episodic memory, in healthy older males and females with age-associated memory impairment (AAMI).

Daily Cognizin® citicoline supplementation also improved motor speed and decreased impulsivity in study participants

Citicoline showed significantly better ability to produce correct responses on the CPT-II, likely due to improved cognitive inhibition. Our findings suggest that citicoline may improve attentional performance in middle-aged women and may ameliorate attentional deficits associated with central nervous system disorders.

These data demonstrate that Citicoline-related alterations in brain neurochemistry are regionally specific and suggest that oral Citicoline administration improves cellular bioenergetics of the anterior cingulate cortex. These findings have important implications, given that maintenance of PCr and beta NTP levels have been shown to be neuroprotective.

This study, carried out by the Consolidated Department of Psychiatry of Harvard Medical School, suggests that the administration of oral citicoline may be of use in reversing age-related changes in the brain

These results suggest that the cytidine moiety of CDP-choline stimulates phosphatidylcholine synthesis in human brain cell membranes in older subjects.

These preliminary findings suggest a potential usefulness of citicoline in modulating appetite, but further research is warranted.

This study, carried out at M.I.T's Clinical Research Center, tested the verbal memory of older volunteers given citicoline and measured its improvement in older individuals with relatively inefficient memories

This study, carried out by the EuroEspes Biomedical Research Center in Spain, concludes that the citicoline molecule is suitable for the treatment of memory deficits in old people

References for further research about Cognizin® citicoline